button cancel
Pokušajte pretraživati po ključnim riječima, kodu narudžbe ili proizvoda ili serijskom broju, npr. „CM442“ ili „tehničke informacije“
Unesite minimalno 2 znaka za pokretanje pretrage.

Raman upstream bioprocess control

Nicro provides turnkey solutions for fermenters

This case study examines how Nicro moved from time-consuming sample analysis to real-time monitoring of critical parameters in their fermentation processes. The result? Inline process monitoring of metabolites without the need of offline sampling helped the company improve process control, leading to optimized production and increased yield.

Bioreactors in Nicro case study ©Endress+Hauser

The results

  • Faster process cycle times with less risk due to in-line,
    real-time process monitoring of metabolites

  • Improved process control leading to optimized
    production and increased yield

  • A complete technology packaged solution for fermentation processes

Customer challenges

A typical indicator of fermentation progress is the lack of dissolved oxygen in the media which gives an estimation of the process duration. Optical density and metabolites may also be monitored for better insight into the process. Concentration of metabolites would usually be measured off-line with time-consuming chromatographic techniques. This off-line sampling approach can bring a potential risk of contamination and lead to the loss of a valuable batch.

Our solution

Nicro combined its competencies together with BICRO BIOCentre and Endress+Hauser to provide a complete packaged solution for fermentation processes. It includes:

  • Engineering and design of a complete fermentation system from Nicro

  • An Endress+Hauser Raman Rxn analyzer and Rxn-45 probe, powered by Kaiser Raman technology

  • Analytical services from BICRO BIOCentre supported by S-PACT modelling services

Read the whole case study

Povezana ponuda

  • Product Picture Raman Rxn2 analyzer view from front showing left side Product Picture Raman Rxn2 analyzer view from front showing left side
    • F
    • L
    • E
    • X

    Raman Rxn2 analyzer

    Bridge your application from the laboratory to the process environment

    Učitavanje cijene
    Cijene privremeno nisu dostupne
    from CHF ??.-
  • Product picture Raman Rxn-45 probe side view aiming right Product picture Raman Rxn-45 probe side view aiming right
    • F
    • L
    • E
    • X

    Raman Rxn-45 probe

    The ultimate in compatibility for bioprocess manufacturing

    Učitavanje cijene
    Cijene privremeno nisu dostupne
    from CHF ??.-

  • Jednostavni proizvodi

  • Jednostavno je odabrati, instalirati i rukovati

Tehnička izvrsnost

Jednostavnost

  • Standardni proizvodi

  • Pouzdano, robustno i s malo održavanja

Tehnička izvrsnost

Jednostavnost

  • Vrhunski proizvodi

  • Izuzetno funkcionalno i prikladno

Tehnička izvrsnost

Jednostavnost

  • Specijalizirani proizvodi

  • Dizajnirano za zahtjevne aplikacije

Tehnička izvrsnost

Jednostavnost

Promjenjivo

FLEX odabir Tehnička izvrsnost Jednostavnost
  • F
  • L
  • E
  • X

Fundamental odabir

Udovoljite svojim osnovnim potrebama u mjernju

Tehnička izvrsnost
Jednostavnost
  • F
  • L
  • E
  • X

Lean odabir

Jednostavno upravljajte svojim osnovnim procesima

Tehnička izvrsnost
Jednostavnost
  • F
  • L
  • E
  • X

Extended odabir

Optimizirajte svoje procese s inovativnim tehnologijama

Tehnička izvrsnost
Jednostavnost
  • F
  • L
  • E
  • X

Xpert odabir

Ovladajte svojim najizazovnijim aplikacijama

Tehnička izvrsnost
Jednostavnost

Promjenjivo

Poštujemo vašu privatnost

Upotrebljavamo kolačiće kako bismo poboljšali vaše iskustvo pretraživanja, prikupljali statističke podatke za optimizaciju funkcionalnosti internetske stranice i omogućili personalizirane oglase ili sadržaj.

Odabirom opcije "Prihvati sve" pristajete na našu upotrebu kolačića.
Za više informacija pročitajte našu Politiku o kolačićima .